Caffeine is a natural stimulant found in coffee, tea, and chocolate, widely used to increase alertness and fight fatigue by blocking adenosine in the brain, speeding up the central nervous system, and improving focus and mood.
Tadalafil, sold under the brand name Cialis among others, is a medication used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension. It is taken by mouth. Onset is typically within half an hour and the duration is up to 36 hours.
3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, and molly, is an entactogen with stimulant and minor psychedelic properties. MDMA was first synthesized in 1912 by Merck chemist Anton Köllisch. It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s.