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3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, and molly, is an entactogen with stimulant and minor psychedelic properties. MDMA was first synthesized in 1912 by Merck chemist Anton Köllisch. It was used to enhance psychotherapy beginning in the 1970s and became popular as a street drug in the 1980s.
Amphetamine is a powerful central nervous system stimulant drug, chemically known as 1-phenylpropan-2-amine, used medically for conditions like ADHD, narcolepsy, and binge eating disorder (as lisdexamfetamine), but also carries abuse potential due to its effects on mood and alertness, with varied forms like methamphetamine and MDMA being well-known relatives, all impacting dopamine and norepinephrine systems.
